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Enzymatic Relay Mechanism Stimulates Cyclic GMP Synthesis in Rod Photoresponse: Biochemical and Physiological Study in Guanylyl Cyclase Activating Protein 1 Knockout Mice
Regulation of cGMP synthesis by retinal membrane guanylyl cyclase isozymes (RetGC1 and RetGC2) in rod and cone photoreceptors by calcium-sensitive guanylyl cyclase activating proteins (GCAP1 and GCAP2) is one of the key molecular mechanisms affecting the response to light and is involved in congenit...
Autores principales: | Makino, Clint L., Wen, Xiao-Hong, Olshevskaya, Elena V., Peshenko, Igor V., Savchenko, Andrey B., Dizhoor, Alexander M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474714/ https://www.ncbi.nlm.nih.gov/pubmed/23082185 http://dx.doi.org/10.1371/journal.pone.0047637 |
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