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A Culture-Independent Approach to Unravel Uncultured Bacteria and Functional Genes in a Complex Microbial Community
Most microorganisms in nature are uncultured with unknown functionality. Sequence-based metagenomics alone answers ‘who/what are there?’ but not ‘what are they doing and who is doing it and how?’. Function-based metagenomics reveals gene function but is usually limited by the specificity and sensiti...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474725/ https://www.ncbi.nlm.nih.gov/pubmed/23082176 http://dx.doi.org/10.1371/journal.pone.0047530 |