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Persurf, a New Method to Improve Surfactant Delivery: A Study in Surfactant Depleted Rats

PURPOSE: Exogenous surfactant is not very effective in adults with ARDS, since surfactant does not reach atelectatic alveoli. Perfluorocarbons (PFC) can recruit atelectatic areas but do not replace impaired endogenous surfactant. A surfactant-PFC-mixture could combine benefits of both therapies. The...

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Detalles Bibliográficos
Autores principales: Burkhardt, Wolfram, Kraft, Stephan, Ochs, Matthias, Proquitté, Hans, Mense, Lars, Rüdiger, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474734/
https://www.ncbi.nlm.nih.gov/pubmed/23082229
http://dx.doi.org/10.1371/journal.pone.0047923