Novel Frataxin Isoforms May Contribute to the Pathological Mechanism of Friedreich Ataxia

Friedreich ataxia (FRDA) is an inherited neurodegenerative disease caused by frataxin (FXN) deficiency. The nervous system and heart are the most severely affected tissues. However, highly mitochondria-dependent tissues, such as kidney and liver, are not obviously affected, although the abundance of...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Haiyan, Cao, Yun, Dai, Xiaoman, Marelja, Zvonimir, Zhou, Di, Mo, Ran, Al-Mahdawi, Sahar, Pook, Mark A., Leimkühler, Silke, Rouault, Tracey A., Li, Kuanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474739/
https://www.ncbi.nlm.nih.gov/pubmed/23082224
http://dx.doi.org/10.1371/journal.pone.0047847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474739/
https://www.ncbi.nlm.nih.gov/pubmed/23082224
http://dx.doi.org/10.1371/journal.pone.0047847

Ejemplares similares