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Genome-Wide Association Identifies Multiple Genomic Regions Associated with Susceptibility to and Control of Ovine Lentivirus

BACKGROUND: Like human immunodeficiency virus (HIV), ovine lentivirus (OvLV) is macrophage-tropic and causes lifelong infection. OvLV infects one quarter of U.S. sheep and induces pneumonia and body condition wasting. There is no vaccine to prevent OvLV infection and no cost-effective treatment for...

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Detalles Bibliográficos
Autores principales: White, Stephen N., Mousel, Michelle R., Herrmann-Hoesing, Lynn M., Reynolds, James O., Leymaster, Kreg A., Neibergs, Holly L., Lewis, Gregory S., Knowles, Donald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474742/
https://www.ncbi.nlm.nih.gov/pubmed/23082221
http://dx.doi.org/10.1371/journal.pone.0047829