Significant Expression Levels of Transgenic PPP1CC2 in Testis and Sperm Are Required to Overcome the Male Infertility Phenotype of Ppp1cc Null Mice

PPP1CC2, one of four isoforms of the ser/thr protein phosphatase PP1, is a mammalian-specific splice variant of the Ppp1cc gene, and the only isoform whose expression is confined almost completely to spermatogenic cells. Additionally, PPP1CC2 is the sole isoform found in mammalian spermatozoa. Altho...

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Detalles Bibliográficos
Autores principales: Sinha, Nilam, Pilder, Stephen, Vijayaraghavan, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474748/
https://www.ncbi.nlm.nih.gov/pubmed/23082183
http://dx.doi.org/10.1371/journal.pone.0047623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474748/
https://www.ncbi.nlm.nih.gov/pubmed/23082183
http://dx.doi.org/10.1371/journal.pone.0047623

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