Enrichment and Stratification for Predementia Alzheimer Disease Clinical Trials

The tau and amyloid pathobiological processes underlying Alzheimer disease (AD) progresses slowly over periods of decades before clinical manifestation as mild cognitive impairment (MCI), then more rapidly to dementia, and eventually to end-stage organ failure. The failure of clinical trials of cand...

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Detalles Bibliográficos
Autores principales: Holland, Dominic, McEvoy, Linda K., Desikan, Rahul S., Dale, Anders M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474753/
https://www.ncbi.nlm.nih.gov/pubmed/23082203
http://dx.doi.org/10.1371/journal.pone.0047739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474753/
https://www.ncbi.nlm.nih.gov/pubmed/23082203
http://dx.doi.org/10.1371/journal.pone.0047739

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