Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator (tPA), ADAMTS-4, ADAMTS-5, and Their Modulators

The extracellular signaling protein Reelin, indispensable for proper neuronal migration and cortical layering during development, is also expressed in the adult brain where it modulates synaptic functions. It has been shown that proteolytic processing of Reelin decreases its signaling activity and p...

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Detalles Bibliográficos
Autores principales: Krstic, Dimitrije, Rodriguez, Myriam, Knuesel, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474754/
https://www.ncbi.nlm.nih.gov/pubmed/23082219
http://dx.doi.org/10.1371/journal.pone.0047793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474754/
https://www.ncbi.nlm.nih.gov/pubmed/23082219
http://dx.doi.org/10.1371/journal.pone.0047793

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