Rereplication in emi1-Deficient Zebrafish Embryos Occurs through a Cdh1-Mediated Pathway

Disruption of early mitotic inhibitor 1 (Emi1) interferes with normal cell cycle progression and results in early embryonic lethality in vertebrates. During S and G2 phases the ubiquitin ligase complex APC/C is inhibited by Emi1 protein, thereby enabling the accumulation of Cyclins A and B so they c...

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Detalles Bibliográficos
Autores principales: Robu, Mara E., Zhang, Yong, Rhodes, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474755/
https://www.ncbi.nlm.nih.gov/pubmed/23082190
http://dx.doi.org/10.1371/journal.pone.0047658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474755/
https://www.ncbi.nlm.nih.gov/pubmed/23082190
http://dx.doi.org/10.1371/journal.pone.0047658

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