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Pharmacogenetic Study of Drug-Metabolising Enzyme Polymorphisms on the Risk of Anti-Tuberculosis Drug-Induced Liver Injury: A Meta-Analysis

BACKGROUND: Three first-line antituberculosis drugs, isoniazid, rifampicin and pyrazinamide, may induce liver injury, especially isoniazid. This antituberculosis drug-induced liver injury (ATLI) ranges from a mild to severe form, and the associated mortality cases are not rare. In the past decade, m...

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Detalles Bibliográficos
Autores principales: Cai, Yu, Yi, JiaYong, Zhou, ChaoHui, Shen, XiZhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474796/
https://www.ncbi.nlm.nih.gov/pubmed/23082213
http://dx.doi.org/10.1371/journal.pone.0047769