Nf1 RasGAP Inhibition of LIMK2 Mediates a New Cross-Talk between Ras and Rho Pathways

BACKGROUND: Ras GTPases mediate numerous biological processes through their ability to cycle between an inactive GDP-bound form and an active GTP-bound form. Guanine nucleotide exchange factors (GEFs) favor the formation of the active Ras-GTP, whereas GTPase activating proteins (GAPs) promote the fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Vallée, Béatrice, Doudeau, Michel, Godin, Fabienne, Gombault, Aurélie, Tchalikian, Aurélie, de Tauzia, Marie-Ludivine, Bénédetti, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474823/
https://www.ncbi.nlm.nih.gov/pubmed/23082153
http://dx.doi.org/10.1371/journal.pone.0047283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474823/
https://www.ncbi.nlm.nih.gov/pubmed/23082153
http://dx.doi.org/10.1371/journal.pone.0047283

Ejemplares similares