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Functional Significance of SRJ Domain Mutations in CITED2

CITED2 is a transcriptional co-activator with 3 conserved domains shared with other CITED family members and a unique Serine-Glycine Rich Junction (SRJ) that is highly conserved in placental mammals. Loss of Cited2 in mice results in cardiac and aortic arch malformations, adrenal agenesis, neural tu...

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Detalles Bibliográficos
Autores principales: Chen, Chiann-mun, Bentham, Jamie, Cosgrove, Catherine, Braganca, Jose, Cuenda, Ana, Bamforth, Simon D., Schneider, Jürgen E., Watkins, Hugh, Keavney, Bernard, Davies, Benjamin, Bhattacharya, Shoumo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474824/
https://www.ncbi.nlm.nih.gov/pubmed/23082118
http://dx.doi.org/10.1371/journal.pone.0046256