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Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly

Nuclear pore complexes (NPCs) fuse the two membranes of the nuclear envelope (NE) to a pore, connecting cytoplasm and nucleoplasm and allowing exchange of macromolecules between these compartments. Most NPC proteins do not contain integral membrane domains and thus it is largely unclear how NPCs are...

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Detalles Bibliográficos
Autores principales: Vollmer, Benjamin, Schooley, Allana, Sachdev, Ruchika, Eisenhardt, Nathalie, Schneider, Anna M, Sieverding, Cornelia, Madlung, Johannes, Gerken, Uwe, Macek, Boris, Antonin, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474928/
https://www.ncbi.nlm.nih.gov/pubmed/22960634
http://dx.doi.org/10.1038/emboj.2012.256