Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model

Anxiety disorders are characterized by persistent, excessive fear. Therapeutic interventions that reverse deficits in fear extinction represent a tractable approach to treating these disorders. We previously reported that 129S1/SvImJ (S1) mice show no extinction learning following normal fear condit...

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Detalles Bibliográficos
Autores principales: Whittle, Nigel, Schmuckermair, Claudia, Gunduz Cinar, Ozge, Hauschild, Markus, Ferraguti, Francesco, Holmes, Andrew, Singewald, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474950/
https://www.ncbi.nlm.nih.gov/pubmed/22722028
http://dx.doi.org/10.1016/j.neuropharm.2012.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474950/
https://www.ncbi.nlm.nih.gov/pubmed/22722028
http://dx.doi.org/10.1016/j.neuropharm.2012.06.001

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