CuAAC Click Chemistry Accelerates the Discovery of Novel Chemical Scaffolds as Promising Protein Tyrosine Phosphatases Inhibitors

Protein tyrosine phosphatases (PTPs) are crucial regulators for numerous biological processes in nature. The dysfunction and overexpression of many PTP members have been demonstrated to cause fatal human diseases such as cancers, diabetes, obesity, neurodegenerative diseases and autoimmune disorders...

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Detalles Bibliográficos
Autores principales: He, X.-P., Xie, J., Tang, Y., Li, J., Chen, G.-R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474962/
https://www.ncbi.nlm.nih.gov/pubmed/22455590
http://dx.doi.org/10.2174/092986712800269245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474962/
https://www.ncbi.nlm.nih.gov/pubmed/22455590
http://dx.doi.org/10.2174/092986712800269245

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