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Genetic variation in histidine rich proteins among Indian Plasmodium falciparum population: possible cause of variable sensitivity of malaria rapid diagnostic tests

BACKGROUND: Rapid diagnostic tests (RDTs) have revolutionized the diagnosis of malaria. Among the various factors affecting RDTs sensitivity is genetic variation of the antigen used. The genetic variation in PfHRP2 and PfHRP3 proteins was studied among the Indian Plasmodium falciparum isolates. METH...

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Detalles Bibliográficos
Autores principales: Kumar, Navin, Singh, Jai PN, Pande, Veena, Mishra, Neelima, Srivastava, Bina, Kapoor, Ridhima, Valecha, Neena, Anvikar, Anupkumar R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475030/
https://www.ncbi.nlm.nih.gov/pubmed/22929537
http://dx.doi.org/10.1186/1475-2875-11-298