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Inhibition of osteoclastogenesis by RNA interference targeting RANK

BACKGROUND: Osteoclasts and osteoblasts regulate bone resorption and formation to allow bone remodeling and homeostasis. The balance between bone resorption and formation is disturbed by abnormal recruitment of osteoclasts. Osteoclast differentiation is dependent on the receptor activator of nuclear...

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Detalles Bibliográficos
Autores principales: Ma, Ruofan, Xu, Jie, Dong, Bin, Kauther, Max Daniel, Jäger, Marcus, Wedemeyer, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475138/
https://www.ncbi.nlm.nih.gov/pubmed/22913338
http://dx.doi.org/10.1186/1471-2474-13-154