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Image-Based Quantification of Benzoporphyrin Derivative Uptake, Localization, and Photobleaching in 3D Tumor Models, for Optimization of PDT Parameters

Photodynamic therapy (PDT) is a light-based treatment modality in which wavelength specific activation of a photosensitizer (PS) generates cytotoxic response in the irradiated region. PDT response is critically dependent on several parameters including light dose, PS dose, uptake time, fluence rate,...

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Detalles Bibliográficos
Autores principales: Glidden, Michael D., Celli, Jonathan P., Massodi, Iqbal, Rizvi, Imran, Pogue, Brian W., Hasan, Tayyaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475211/
https://www.ncbi.nlm.nih.gov/pubmed/23082096
http://dx.doi.org/10.7150/thno.4334