Evidence for Transcriptional Factor Dysregulation in the Dorsal Raphe Nucleus of Patients with Major Depressive Disorder

Extensive evidence implicates dysfunction in serotonin (5-HT) signaling in the etiology of major depressive disorder (MDD). Dorsal raphe nucleus (DR) is a major source of serotonin in the brain, and previous studies have reported within it alterations in 5-HT-related gene expression, protein levels,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kerman, Ilan A., Bernard, René, Bunney, William E., Jones, Edward G., Schatzberg, Alan F., Myers, Richard M., Barchas, Jack D., Akil, Huda, Watson, Stanley J., Thompson, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475304/
https://www.ncbi.nlm.nih.gov/pubmed/23087602
http://dx.doi.org/10.3389/fnins.2012.00135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475304/
https://www.ncbi.nlm.nih.gov/pubmed/23087602
http://dx.doi.org/10.3389/fnins.2012.00135

Ejemplares similares