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Evidence for Transcriptional Factor Dysregulation in the Dorsal Raphe Nucleus of Patients with Major Depressive Disorder
Extensive evidence implicates dysfunction in serotonin (5-HT) signaling in the etiology of major depressive disorder (MDD). Dorsal raphe nucleus (DR) is a major source of serotonin in the brain, and previous studies have reported within it alterations in 5-HT-related gene expression, protein levels,...
Autores principales: | Kerman, Ilan A., Bernard, René, Bunney, William E., Jones, Edward G., Schatzberg, Alan F., Myers, Richard M., Barchas, Jack D., Akil, Huda, Watson, Stanley J., Thompson, Robert C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475304/ https://www.ncbi.nlm.nih.gov/pubmed/23087602 http://dx.doi.org/10.3389/fnins.2012.00135 |
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