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Mitochondrial dysfunction in insulin resistance: differential contributions of chronic insulin and saturated fatty acid exposure in muscle cells

Mitochondrial dysfunction has been associated with insulin resistance, obesity and diabetes. Hyperinsulinaemia and hyperlipidaemia are hallmarks of the insulin-resistant state. We sought to determine the contributions of high insulin and saturated fatty acid exposure to mitochondrial function and bi...

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Detalles Bibliográficos
Autores principales: Yang, Chenjing, Aye, Cho Cho, Li, Xiaoxin, Diaz Ramos, Angels, Zorzano, Antonio, Mora, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475448/
https://www.ncbi.nlm.nih.gov/pubmed/22742515
http://dx.doi.org/10.1042/BSR20120034