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CXCL12/SDF-1α Activates NF-κB and Promotes Oral Cancer Invasion through the Carma3/Bcl10/Malt1 Complex

AIM: To determine how SDF-1α/CXCR4 activates nuclear factor-kappa B (NF-κB) and promotes oral squamous cell carcinoma (OSCC) invasion. METHODOLOGY: A lentivirus-based knockdown approach was utilized to deplete gene expression. NF-κB activation was evaluated by Western blot analysis and electrophoret...

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Detalles Bibliográficos
Autores principales: Rehman, Aasia O, Wang, Cun-yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475585/
https://www.ncbi.nlm.nih.gov/pubmed/20695076
http://dx.doi.org/10.4248/IJOS.09059