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Regulatory Network Structure as a Dominant Determinant of Transcription Factor Evolutionary Rate
The evolution of transcriptional regulatory networks has thus far mostly been studied at the level of cis-regulatory elements. To gain a complete understanding of regulatory network evolution we must also study the evolutionary role of trans-factors, such as transcription factors (TFs). Here, we sys...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475661/ https://www.ncbi.nlm.nih.gov/pubmed/23093926 http://dx.doi.org/10.1371/journal.pcbi.1002734 |