Determining Host Metabolic Limitations on Viral Replication via Integrated Modeling and Experimental Perturbation

Viral replication relies on host metabolic machinery and precursors to produce large numbers of progeny - often very rapidly. A fundamental example is the infection of Escherichia coli by bacteriophage T7. The resource draw imposed by viral replication represents a significant and complex perturbati...

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Detalles Bibliográficos
Autores principales: Birch, Elsa W., Ruggero, Nicholas A., Covert, Markus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475664/
https://www.ncbi.nlm.nih.gov/pubmed/23093930
http://dx.doi.org/10.1371/journal.pcbi.1002746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475664/
https://www.ncbi.nlm.nih.gov/pubmed/23093930
http://dx.doi.org/10.1371/journal.pcbi.1002746

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