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Determining Host Metabolic Limitations on Viral Replication via Integrated Modeling and Experimental Perturbation
Viral replication relies on host metabolic machinery and precursors to produce large numbers of progeny - often very rapidly. A fundamental example is the infection of Escherichia coli by bacteriophage T7. The resource draw imposed by viral replication represents a significant and complex perturbati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475664/ https://www.ncbi.nlm.nih.gov/pubmed/23093930 http://dx.doi.org/10.1371/journal.pcbi.1002746 |