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The Respiratory Syncytial Virus Polymerase Has Multiple RNA Synthesis Activities at the Promoter

Respiratory syncytial virus (RSV) is an RNA virus in the Family Paramyxoviridae. Here, the activities performed by the RSV polymerase when it encounters the viral antigenomic promoter were examined. RSV RNA synthesis was reconstituted in vitro using recombinant, isolated polymerase and an RNA oligon...

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Detalles Bibliográficos
Autores principales: Noton, Sarah L., Deflubé, Laure R., Tremaglio, Chadene Z., Fearns, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475672/
https://www.ncbi.nlm.nih.gov/pubmed/23093940
http://dx.doi.org/10.1371/journal.ppat.1002980