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Leishmania donovani Argininosuccinate Synthase Is an Active Enzyme Associated with Parasite Pathogenesis

BACKGROUND: Gene expression analysis in Leishmania donovani (Ld) identified an orthologue of the urea cycle enzyme, argininosuccinate synthase (LdASS), that was more abundantly expressed in amastigotes than in promastigotes. In order to characterize in detail this newly identified protein in Leishma...

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Detalles Bibliográficos
Autores principales: Lakhal-Naouar, Ines, Jardim, Armando, Strasser, Rona, Luo, Shen, Kozakai, Yukiko, Nakhasi, Hira L., Duncan, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475689/
https://www.ncbi.nlm.nih.gov/pubmed/23094117
http://dx.doi.org/10.1371/journal.pntd.0001849