Global Protein Conjugation by Ubiquitin-Like-Modifiers during Ischemic Stress Is Regulated by MicroRNAs and Confers Robust Tolerance to Ischemia

Hibernation torpor provides an excellent model of natural tolerance to ischemia. We have previously shown that massive global SUMOylation occurs during hibernation torpor in ground squirrels. We have also shown that overexpression of Ubc9, SUMO-1, or SUMO-2/3 provides protection against ischemic dam...

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Detalles Bibliográficos
Autores principales: Lee, Yang-ja, Johnson, Kory R., Hallenbeck, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475703/
https://www.ncbi.nlm.nih.gov/pubmed/23094087
http://dx.doi.org/10.1371/journal.pone.0047787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475703/
https://www.ncbi.nlm.nih.gov/pubmed/23094087
http://dx.doi.org/10.1371/journal.pone.0047787

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