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Initiation of transcription-coupled repair characterized at single-molecule resolution

Transcription-coupled repair employs components of the transcription machinery to identify DNA lesions and initiate their repair. These repair pathways are complex so their mechanistic features remain poorly understood. Bacterial transcription-coupled repair is initiated when RNA polymerase stalled...

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Detalles Bibliográficos
Autores principales: Wan, Kévin Ho, Smith, Abigail, Westblade, Lars, Joly, Nicolas, Grange, Wilfried, Zorman, Sylvain, Darst, Seth, Savery, Nigel, Strick, Terence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475728/
https://www.ncbi.nlm.nih.gov/pubmed/22960746
http://dx.doi.org/10.1038/nature11430