Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion

Perturbation of Disrupted-In-Schizophrenia-1 (DISC1) and D-serine/NMDA receptor hypofunction have both been implicated in the pathophysiology of schizophrenia and other psychiatric disorders. In the present study, we demonstrate that these two pathways intersect with behavioral consequences. DISC1 b...

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Detalles Bibliográficos
Autores principales: Ma, T.M., Abazyan, S., Abazyan, B., Nomura, J., Yang, C., Seshadri, S., Sawa, A., Snyder, S.H., Pletnikov, M.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475769/
https://www.ncbi.nlm.nih.gov/pubmed/22801410
http://dx.doi.org/10.1038/mp.2012.97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475769/
https://www.ncbi.nlm.nih.gov/pubmed/22801410
http://dx.doi.org/10.1038/mp.2012.97

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