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Increased activity of serotonin uptake in platelets in medication overuse headache following regular intake of analgesics and triptans

We investigated the effect of chronic administration of different pain medications on the activity of the serotonin transporter (SERT) in patients with medication overuse headache (MOH). We measured the kinetic of platelet 5-HT uptake (maximal velocity, V(max) and the Michaelis–Menten constant, K(m)...

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Detalles Bibliográficos
Autores principales: Ayzenberg, Ilya, Oberman, Mark, Leineweber, Kirsten, Franke, Leonora, Yoon, Min-Suk, Diener, Hans-Christoph, Katsarava, Zaza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476187/
https://www.ncbi.nlm.nih.gov/pubmed/18330504
http://dx.doi.org/10.1007/s10194-008-0019-9