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Is there an inherent limit to the efficacy of calcitonin gene-related peptide receptor antagonists in the acute treatment of migraine? A comment

Calcitonin gene-related peptide (CGRP) receptor antagonists are a new treatment principle in acute migraine attacks. Intravenous olcegepant 2.5 mg resulted in 66% headache relief after 2 h, whereas subcutaneous sumatriptan resulted in 81–92% headache relief after 2 h. The intrinsic activity of a par...

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Detalles Bibliográficos
Autor principal: Tfelt-Hansen, Peer C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476212/
https://www.ncbi.nlm.nih.gov/pubmed/19779958
http://dx.doi.org/10.1007/s10194-009-0157-8