Demonstration of Phosphoryl Group Transfer Indicates That the ATP-binding Cassette (ABC) Transporter Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Exhibits Adenylate Kinase Activity

Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane-spanning adenosine 5′-triphosphate (ATP)-binding cassette (ABC) transporter. ABC transporters and other nuclear and cytoplasmic ABC proteins have ATPase activity that is coupled to their biological function. Recent studies with...

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Detalles Bibliográficos
Autores principales: Randak, Christoph O., Ver Heul, Amanda R., Welsh, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476278/
https://www.ncbi.nlm.nih.gov/pubmed/22948143
http://dx.doi.org/10.1074/jbc.M112.408450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476278/
https://www.ncbi.nlm.nih.gov/pubmed/22948143
http://dx.doi.org/10.1074/jbc.M112.408450

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