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Facilitating Drug Discovery: An Automated High-content Inflammation Assay in Zebrafish

Zebrafish larvae are particularly amenable to whole animal small molecule screens(1,2) due to their small size and relative ease of manipulation and observation, as well as the fact that compounds can simply be added to the bathing water and are readily absorbed when administered in a <1% DMSO so...

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Detalles Bibliográficos
Autores principales: Wittmann, Christine, Reischl, Markus, Shah, Asmi H., Mikut, Ralf, Liebel, Urban, Grabher, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476412/
https://www.ncbi.nlm.nih.gov/pubmed/22825322
http://dx.doi.org/10.3791/4203