Synergy of Peptide and Sugar in O-GlcNAcase Substrate Recognition

Protein O-GlcNAcylation is an essential reversible posttranslational modification in higher eukaryotes. O-GlcNAc addition and removal is catalyzed by O-GlcNAc transferase and O-GlcNAcase, respectively. We report the molecular details of the interaction of a bacterial O-GlcNAcase homolog with three d...

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Detalles Bibliográficos
Autores principales: Schimpl, Marianne, Borodkin, Vladimir S., Gray, Lindsey J., van Aalten, Daan M.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476531/
https://www.ncbi.nlm.nih.gov/pubmed/22365600
http://dx.doi.org/10.1016/j.chembiol.2012.01.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476531/
https://www.ncbi.nlm.nih.gov/pubmed/22365600
http://dx.doi.org/10.1016/j.chembiol.2012.01.011

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