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Altered Phenotype of Peripheral Blood Dendritic Cells in Pediatric Type 1 Diabetes

OBJECTIVE: Dendritic cells (DCs) are largely responsible for the activation and fine-tuning of T-cell responses. Altered numbers of blood DCs have been reported in type 1 diabetes (T1D). We aimed at characterizing the less well-known phenotypic properties of DCs in T1D. RESEARCH DESIGN AND METHODS:...

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Detalles Bibliográficos
Autores principales: Nieminen, Janne K., Vakkila, Jukka, Salo, Harri M., Ekström, Nina, Härkönen, Taina, Ilonen, Jorma, Knip, Mikael, Vaarala, Outi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476907/
https://www.ncbi.nlm.nih.gov/pubmed/22787171
http://dx.doi.org/10.2337/dc11-2460