Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome

BACKGROUND: Aberrant promoter CpG island hypermethylation is associated with transcriptional silencing. Tumor suppressor genes are the key targets of hypermethylation in breast cancer and therefore may lead to malignancy by deregulation of cell growth and division. Our previous pilot study with pair...

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Detalles Bibliográficos
Autores principales: Xu, Jia, Shetty, Priya B, Feng, Weiwei, Chenault, Carol, Bast, Robert C, Hilsenbeck, Susan G, Yu, Yinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476972/
https://www.ncbi.nlm.nih.gov/pubmed/22695491
http://dx.doi.org/10.1186/1471-2407-12-243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476972/
https://www.ncbi.nlm.nih.gov/pubmed/22695491
http://dx.doi.org/10.1186/1471-2407-12-243

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