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Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation
BACKGROUND: The Tax protein encoded by Human T-lymphotropic virus type 1 (HTLV-1) is a powerful activator of the NF-κB pathway, a property critical for HTLV-1-induced immortalization of CD4(+) T lymphocytes. Tax permanently stimulates this pathway at a cytoplasmic level by activating the IκB kinase...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476979/ https://www.ncbi.nlm.nih.gov/pubmed/23009398 http://dx.doi.org/10.1186/1742-4690-9-77 |