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The influence of the combined treatment with Vadimezan (ASA404) and taxol on the growth of U251 glioblastoma xenografts

BACKGROUND: One of the most important biological characteristics of Glioblastoma multiforme (GBM) is high vascular density. Vadimezan (ASA404, DMXAA) belongs to the class of small molecule vascular disrupting agents (VDA) that cause disruption of established tumor vessels and subsequent tumor hemorr...

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Detalles Bibliográficos
Autores principales: Milanović, Dušan, Braun, Friederike, Weber, Wolfgang, Grosu, Anca Ligia, Behe, Martin, Niedermann, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476988/
https://www.ncbi.nlm.nih.gov/pubmed/22695475
http://dx.doi.org/10.1186/1471-2407-12-242