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Combined analysis of genome-wide expression and copy number profiles to identify key altered genomic regions in cancer

BACKGROUND: Analysis of DNA copy number alterations and gene expression changes in human samples have been used to find potential target genes in complex diseases. Recent studies have combined these two types of data using different strategies, but focusing on finding gene-based relationships. Howev...

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Detalles Bibliográficos
Autores principales: Fontanillo, Celia, Aibar, Sara, Sanchez-Santos, Jose Manuel, De Las Rivas, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476997/
https://www.ncbi.nlm.nih.gov/pubmed/23095915
http://dx.doi.org/10.1186/1471-2164-13-S5-S5