B7h-expressing dendritic cells and plasma B cells mediate distinct outcomes of ICOS costimulation in T cell-dependent antibody responses

BACKGROUND: The ICOS-B7h costimulatory receptor-ligand pair is required for germinal center formation, the production of isotype-switched antibodies, and antibody affinity maturation in response to T cell-dependent antigens. However, the potentially distinct roles of regulated B7h expression on B ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Larimore, Kevin, Liang, Linda, Bakkour, Sonia, Sha, William C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477010/
https://www.ncbi.nlm.nih.gov/pubmed/22686515
http://dx.doi.org/10.1186/1471-2172-13-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477010/
https://www.ncbi.nlm.nih.gov/pubmed/22686515
http://dx.doi.org/10.1186/1471-2172-13-29

Ejemplares similares