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B7h-expressing dendritic cells and plasma B cells mediate distinct outcomes of ICOS costimulation in T cell-dependent antibody responses

BACKGROUND: The ICOS-B7h costimulatory receptor-ligand pair is required for germinal center formation, the production of isotype-switched antibodies, and antibody affinity maturation in response to T cell-dependent antigens. However, the potentially distinct roles of regulated B7h expression on B ce...

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Detalles Bibliográficos
Autores principales:	Larimore, Kevin, Liang, Linda, Bakkour, Sonia, Sha, William C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477010/ https://www.ncbi.nlm.nih.gov/pubmed/22686515 http://dx.doi.org/10.1186/1471-2172-13-29

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