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A genome-wide survey for prion-regulated miRNAs associated with cholesterol homeostasis

BACKGROUND: Prion diseases are neurodegenerative diseases that are characterized by the conversion of the cellular prion protein (PrP(c)) into a pathogenic isoform (PrP(Sc)). It is known that neurodegeneration is often accompanied by the disturbance of cholesterol homeostasis. We have recently ident...

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Detalles Bibliográficos
Autores principales: Montag, Judith, Brameier, Markus, Schmädicke, Ann-Christin, Gilch, Sabine, Schätzl, Hermann M, Motzkus, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477035/
https://www.ncbi.nlm.nih.gov/pubmed/22985096
http://dx.doi.org/10.1186/1471-2164-13-486