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A genome-wide survey for prion-regulated miRNAs associated with cholesterol homeostasis
BACKGROUND: Prion diseases are neurodegenerative diseases that are characterized by the conversion of the cellular prion protein (PrP(c)) into a pathogenic isoform (PrP(Sc)). It is known that neurodegeneration is often accompanied by the disturbance of cholesterol homeostasis. We have recently ident...
Autores principales: | Montag, Judith, Brameier, Markus, Schmädicke, Ann-Christin, Gilch, Sabine, Schätzl, Hermann M, Motzkus, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477035/ https://www.ncbi.nlm.nih.gov/pubmed/22985096 http://dx.doi.org/10.1186/1471-2164-13-486 |
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