Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology

BACKGROUND: Alzheimer’s disease (AD) is the leading cause of dementia among the elderly. Disease modifying therapies targeting Aβ that are in development have been proposed to be more effective if treatment was initiated prior to significant accumulation of Aβ in the brain, but optimal timing of tre...

Descripción completa

Detalles Bibliográficos
Autores principales: Das, Pritam, Verbeeck, Christophe, Minter, Lisa, Chakrabarty, Paramita, Felsenstein, Kevin, Kukar, Thomas, Maharvi, Ghulam, Fauq, Abdul, Osborne, Barbara A, Golde, Todd E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477045/
https://www.ncbi.nlm.nih.gov/pubmed/22892055
http://dx.doi.org/10.1186/1750-1326-7-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477045/
https://www.ncbi.nlm.nih.gov/pubmed/22892055
http://dx.doi.org/10.1186/1750-1326-7-39

Ejemplares similares