Cargando…

Hyperglycaemia Exacerbates Choroidal Neovascularisation in Mice via the Oxidative Stress-Induced Activation of STAT3 Signalling in RPE Cells

Choroidal neovascularisation (CNV) that occurs as a result of age-related macular degeneration (AMD) causes severe vision loss among elderly patients. The relationship between diabetes and CNV remains controversial. However, oxidative stress plays a critical role in the pathogenesis of both AMD and...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xia, Cai, Yan, Wang, Yu-Sheng, Shi, Yuan-Yuan, Hou, Wei, Xu, Chun-Sheng, Wang, Hai-Yan, Ye, Zi, Yao, Li-Bo, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477109/
https://www.ncbi.nlm.nih.gov/pubmed/23094067
http://dx.doi.org/10.1371/journal.pone.0047600