Humanized Mouse Model of Skin Inflammation Is Characterized by Disturbed Keratinocyte Differentiation and Influx of IL-17A Producing T Cells

Humanized mouse models offer a challenging possibility to study human cell function in vivo. In the huPBL-SCID-huSkin allograft model human skin is transplanted onto immunodeficient mice and allowed to heal. Thereafter allogeneic human peripheral blood mononuclear cells are infused intra peritoneall...

Descripción completa

Detalles Bibliográficos
Autores principales: de Oliveira, Vivian L., Keijsers, Romy R. M. C., van de Kerkhof, Peter C. M., Seyger, Marieke M. B., Fasse, Esther, Svensson, Lars, Latta, Markus, Norsgaard, Hanne, Labuda, Tord, Hupkens, Pieter, van Erp, Piet E. J., Joosten, Irma, Koenen, Hans J. P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477148/
https://www.ncbi.nlm.nih.gov/pubmed/23094018
http://dx.doi.org/10.1371/journal.pone.0045509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477148/
https://www.ncbi.nlm.nih.gov/pubmed/23094018
http://dx.doi.org/10.1371/journal.pone.0045509

Ejemplares similares