Inhibition of Hepatitis B Virus and Induction of Hepatoma Cell Apoptosis by ASGPR-Directed Delivery of shRNAs

Hepatitis B virus (HBV) infection is a worldwide liver disease and nearly 25% of chronic HBV infections terminate in hepatocellular carcinoma (HCC). Currently, there is no effective therapy to inhibit HBV replication and to eliminate hepatoma cells, making it highly desired to develop novel therapie...

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Detalles Bibliográficos
Autores principales: Ma, Jingwei, Huang, Chunmei, Yao, Xinxin, Shi, Chuan, Sun, Lifang, Yuan, Lu, Lei, Ping, Zhu, Huifen, Liu, Hongbo, Wu, Xiongwen, Ning, Qin, Zhou, Chun, Shen, Guanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477153/
https://www.ncbi.nlm.nih.gov/pubmed/23094023
http://dx.doi.org/10.1371/journal.pone.0046096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477153/
https://www.ncbi.nlm.nih.gov/pubmed/23094023
http://dx.doi.org/10.1371/journal.pone.0046096

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