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Exosomal Lipids Impact Notch Signaling and Induce Death of Human Pancreatic Tumoral SOJ-6 Cells

Exosomes are of increasing interest as alternative mode of cell-to-cell communication. We previously reported that exosomes secreted by human SOJ-6 pancreatic tumor cells induce (glyco)protein ligand-independent cell death and inhibit Notch-1 pathway, this latter being particularly active during car...

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Detalles Bibliográficos
Autores principales: Beloribi, Sadia, Ristorcelli, Elodie, Breuzard, Gilles, Silvy, Françoise, Bertrand-Michel, Justine, Beraud, Evelyne, Verine, Alain, Lombardo, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477155/
https://www.ncbi.nlm.nih.gov/pubmed/23094054
http://dx.doi.org/10.1371/journal.pone.0047480