APE1/Ref-1 Regulates STAT3 Transcriptional Activity and APE1/Ref-1–STAT3 Dual-Targeting Effectively Inhibits Pancreatic Cancer Cell Survival

Pancreatic cancer is a largely incurable disease, and increasing evidence supports strategies targeting multiple molecular mediators of critical functions of pancreatic ductal adenocarcinoma cells. Intracellular redox state modulates the activity of various signal transduction pathways and biologica...

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Detalles Bibliográficos
Autores principales: Cardoso, Angelo A., Jiang, Yanlin, Luo, Meihua, Reed, April M., Shahda, Safi, He, Ying, Maitra, Anirban, Kelley, Mark R., Fishel, Melissa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477158/
https://www.ncbi.nlm.nih.gov/pubmed/23094050
http://dx.doi.org/10.1371/journal.pone.0047462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477158/
https://www.ncbi.nlm.nih.gov/pubmed/23094050
http://dx.doi.org/10.1371/journal.pone.0047462

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